Rex C. Haydon, MD PhD

Rex Haydon, MD, PhD, focuses on the comprehensive treatment of malignant and benign tumors in bone or soft tissue. He specializes in the surgical care of bone and soft tissue tumors, including limb-salvage and reconstructive surgery of the upper and lower extremities. Dr. Haydon works with an integrated team of specialists to ensure that patients have access to the most innovative and effective treatment options available.



Also a skilled physician scientist, his research focuses on advancing the treatment of musculoskeletal tumors. Dr. Haydon has a particular interest in the underlying causes of musculoskeletal neoplasms. Author of more than 25 articles and book chapters, he has accepted career development awards from both the Orthopaedic Research and Education Foundation and the National Institutes of Health. Additionally, Dr. Haydon's research has been supported by the Musculoskeletal Tumor Foundation.

The University of Chicago
Chicago, Illinois
Orthopaedic Fellowship - Oncology
2003

The University of Chicago
Chicago, Illinois
Orthopaedic Fellowship - Research
2002

The University of Chicago
Chicago, Illinois
Resident - Orthopaedic Surgery
2001

The University of Chicago
Chicago, Illinois
Ph.D - Anthropology
1996

The University of Chicago
Chicago, Illinois
M.A. - MAPSS (Social Sciences),
1993

The University of Chicago
Chicago, Illinois
B.A. - Anthropology
1988

Thromboembolic Disease in Patients with Metastatic Femoral Lesions: A Comparison Between Prophylactic Fixation and Fracture Fixation.
Aneja A, Jiang JJ, Cohen-Rosenblum A, Luu HL, Peabody TD, Attar S, Luo TD, Haydon RC. Thromboembolic Disease in Patients with Metastatic Femoral Lesions: A Comparison Between Prophylactic Fixation and Fracture Fixation. J Bone Joint Surg Am. 2017 Feb 15; 99(4):315-323.
PMID: 28196033

Ewing's sarcoma of bone.
Moore DD, Haydon RC. Ewing's sarcoma of bone. Cancer Treat Res. 2014; 162:93-115.
PMID: 25070232

The clinical evaluation of soft tissue tumors.
Balach T, Stacy GS, Haydon RC. The clinical evaluation of soft tissue tumors. Radiol Clin North Am. 2011 Nov; 49(6):1185-96, vi.
PMID: 22024294

Multiplanar osteotomy with limited wide margins: a tissue preserving surgical technique for high-grade bone sarcomas.
Avedian RS, Haydon RC, Peabody TD. Multiplanar osteotomy with limited wide margins: a tissue preserving surgical technique for high-grade bone sarcomas. Clin Orthop Relat Res. 2010 Oct; 468(10):2754-64.
PMID: 20419483

AOA 2005 John J. Fahey, MD, Memorial North American Traveling Fellowship: Fellows' Travel Diary.
Provencher MT, Bozic KJ, Haydon R, Lau JT, Vallier HA. AOA 2005 John J. Fahey, MD, Memorial North American Traveling Fellowship: Fellows' Travel Diary. J Bone Joint Surg Am. 2008 Jan; 90(1):205-7.
PMID: 18171976

Tyrosine kinase inhibitor STI-571: the new wonder drug of cancer therapy.
Haydon RC, Zhou L, He TC. Tyrosine kinase inhibitor STI-571: the new wonder drug of cancer therapy. Cancer Biol Ther. 2004 Apr; 3(4):393-4.
PMID: 15004535

Fluorescence-based functional assay for Wnt/beta-catenin signaling activity.
Zhou L, An N, Jiang W, Haydon R, Cheng H, Zhou Q, Breyer B, Feng T, He TC. Fluorescence-based functional assay for Wnt/beta-catenin signaling activity. Biotechniques. 2002 Nov; 33(5):1126-8, 1130, 1132 passim.
PMID: 12449394

Increased efficiency of cloning large DNA fragments using a lower copy number plasmid.
Feng T, Li Z, Jiang W, Breyer B, Zhou L, Cheng H, Haydon RC, Ishikawa A, Joudeh MA, He TC. Increased efficiency of cloning large DNA fragments using a lower copy number plasmid. Biotechniques. 2002 May; 32(5):992, 994, 996 passim.
PMID: 12019795

Are second-generation antihistamines appropriate for most children and adults?
Haydon RC. Are second-generation antihistamines appropriate for most children and adults? Arch Otolaryngol Head Neck Surg. 2001 Dec; 127(12):1510-3.
PMID: 11735828

Tetracycline-regulated gene expression mediated by a novel chimeric repressor that recruits histone deacetylases in mammalian cells.
Jiang W, Zhou L, Breyer B, Feng T, Cheng H, Haydon R, Ishikawa A, He TC. Tetracycline-regulated gene expression mediated by a novel chimeric repressor that recruits histone deacetylases in mammalian cells. J Biol Chem. 2001 Nov 30; 276(48):45168-74.
PMID: 11581265

View All Publications

Orlov Visiting Professor in Orthopaedic Oncology
Loyola University of Chicago
2018

Senior Faculty Scholar
Bucksbaum Institute for Clinical Excellence
2017

Gerald S. Laros Resident Teaching Award
2011

Keynote Speaker
Pritzker School of Medicine White Coat Ceremony
2010

American-British-Canadian Traveling Fellowship, AOA
2009

Induction into ??? (Beta Chapter) as Faculty member by Pritzker School of Medicine
2008

Gerald S. Laros Resident Teaching Award
2007

Orthopaedic Research Society Career Development Award
2006

Kappa Delta Ann Doner Vaughan Award, Co-Recipient, AAOS/ORS
2006

Marshall R. Urist Young Investigator Award, Association of Bone & Joint Surgeons
2006

John J. Fahey, MD Memorial North American Traveling Fellowship, AOA
2005

K08 Mentored Clinical Scientist Development Award, NIH-NIAMS
2004 - 2009

Thomas M. Coffman OREF Career Development Award
2003 - 2005

Best Poster Award: Charles Huggins Conference: “Upregulation Of cKit In Giant Cell Tumor of Bone: Po
2002

Howard Schneider Award for Best Manuscript at the OREF Midwest Conference
2000