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Research

Foot and Ankle Research

Dr. Brian Toolan has focused on several clinical projects related to foot and ankle disorders. In the past, he studied the effects of acquired flatfoot deformity on tibiotalar contact pressures in a cadaveric model, and performed a follow-up study on the effects of UCBL orthotics and surgical techniques on joint contact characteristics in the same model. Both of these studies were published in Foot & Ankle International. He recently published a retrospective study in Foot & Ankle International comparing lateral column lengthening to a medial calcaneal osteotomy in the treatment of adult acquired flatfoot. He is currently conducted a similar comparison in a prospective clinical study that is currently ongoing.  Lastly, he is retrospectively evaluating the results of a new procedure for salvaging malunited ankle fractures with chronic syndesmotic disruption using a distal fibular arthrodesis and soft tissue reconstructions.

In addition to his interests on flatfoot deformity, Dr. Brian Toolan is interested developing a better understanding of ruptured Achilles tendon healing process and potentially developing new means in treating patients with this injury. Achilles tendon ruptures are common injuries and both surgical and non-surgical treatments have frequent complications such as wound dehiscence and re-rupture. Therefore, Dr. Toolan, in collaboration with Drs. He, has used a rat model to investigate the effects of BMP-14 and other factors on Achilles tendon healing, finding a 70% increase in tensile strength at two weeks. 

Tong-Chuan He, MD PhD

Associate Professor of Orthopedic Surgery and Rehabilitation Medicine
Committee on Cancer Biology
Committee on Genetics, Genomics and Systems Biology