Mostafa El Dafrawy, MBBCh

Orthopaedic surgeon Mostafa El Dafrawy, MBBCh, provides comprehensive spine care to patients with a wide range of spine conditions. Dr. El Dafrawy specializes in complex spinal deformities, spine trauma, degenerative disorders of the cervical and thoraco-lumbar spine, and spinal tumors.



With his expertise in revision spine surgery and spinal reconstruction, Dr. El Dafrawy enhances the lives of his patients by restoring mobility and reducing back pain. He is thrilled to be able to offer spine deformity surgeries and revision surgeries for patients who had a failed back surgery or developed flat back syndrome.



As a physician-scientist, Dr. El Dafrawy is also committed to using basic, clinical and transitional research to investigate novel therapies for spine patients to improve their overall quality of life. His research interests include: adult degenerative scoliosis, kyphoscoliosis and flat back deformities as well as spine tumors, particularly the treatment and management of metastatic spine disease. He has authored numerous research publications and book chapters, and his work has been published in highly respected, peer-reviewed journals, such as Spine, Journal of Bone and Joint Surgery, Spine Deformity, Journal of Neurosurgery Spine and Orthopedics.

Washington University in Saint Louis
Saint Louis
Spine Surgery Fellowship - Complex Adult and Pediatric Spine reconstruction
2019

The Johns Hopkins University Hospital
Baltimore, MD
Orthopaedic Surgery Residency - Orthopaedic Surgery
2018

The Johns Hopkins University Hospital
Baltimore, MD
General Surgery Internship - General Surgery Internship
2013

The Johns Hopkins University
Baltimore, MD
Research Fellowship - Spine Surgery Research Fellowship
2012

Cairo University Hospital
Cairo, Egypt
Orthopaedic Surgery Residency - Orthopaedic Surgery
2010

Migration of an Anterior Cervical Discectomy and Fusion Screw into the Constrictor Muscle of the Hypopharynx: A Case Report.
Dahm J, Nwaudo D, Gooi Z, Lee M, El Dafrawy M. Migration of an Anterior Cervical Discectomy and Fusion Screw into the Constrictor Muscle of the Hypopharynx: A Case Report. JBJS Case Connect. 2021 05 19; 11(2).
PMID: 34010178

The Influence of Selective Serotonin Reuptake Inhibitors on Lumbar Arthrodesis.
Pirkle S, Bhattacharjee S, El Dafrawy M, Leucht P, Shi LL, Lee MJ. The Influence of Selective Serotonin Reuptake Inhibitors on Lumbar Arthrodesis. Clin Spine Surg. 2021 05 01; 34(4):E200-E204.
PMID: 32991364

Applications of Biocompatible Scaffold Materials in Stem Cell-Based Cartilage Tissue Engineering.
Zhao X, Hu DA, Wu D, He F, Wang H, Huang L, Shi D, Liu Q, Ni N, Pakvasa M, Zhang Y, Fu K, Qin KH, Li AJ, Hagag O, Wang EJ, Sabharwal M, Wagstaff W, Reid RR, Lee MJ, Wolf JM, El Dafrawy M, Hynes K, Strelzow J, Ho SH, He TC, Athiviraham A. Applications of Biocompatible Scaffold Materials in Stem Cell-Based Cartilage Tissue Engineering. Front Bioeng Biotechnol. 2021; 9:603444.
PMID: 33842441

BMP9-initiated osteogenic/odontogenic differentiation of mouse tooth germ mesenchymal cells (TGMCS) requires Wnt/ß-catenin signalling activity.
Luo W, Zhang L, Huang B, Zhang H, Zhang Y, Zhang F, Liang P, Chen Q, Cheng Q, Tan D, Tan Y, Song J, Zhao T, Haydon RC, Reid RR, Luu HH, Lee MJ, El Dafrawy M, Ji P, He TC, Gou L. BMP9-initiated osteogenic/odontogenic differentiation of mouse tooth germ mesenchymal cells (TGMCS) requires Wnt/ß-catenin signalling activity. J Cell Mol Med. 2021 03; 25(5):2666-2678.
PMID: 33605035

Long-term rates of bladder dysfunction after decompression in patients with cauda equina syndrome.
Seidel H, Bhattacharjee S, Pirkle S, Shi L, Strelzow J, Lee M, El Dafrawy M. Long-term rates of bladder dysfunction after decompression in patients with cauda equina syndrome. Spine J. 2021 05; 21(5):803-809.
PMID: 33434651

Stem Cell-Friendly Scaffold Biomaterials: Applications for Bone Tissue Engineering and Regenerative Medicine.
Zhang Y, Wu D, Zhao X, Pakvasa M, Tucker AB, Luo H, Qin KH, Hu DA, Wang EJ, Li AJ, Zhang M, Mao Y, Sabharwal M, He F, Niu C, Wang H, Huang L, Shi D, Liu Q, Ni N, Fu K, Chen C, Wagstaff W, Reid RR, Athiviraham A, Ho S, Lee MJ, Hynes K, Strelzow J, He TC, El Dafrawy M. Stem Cell-Friendly Scaffold Biomaterials: Applications for Bone Tissue Engineering and Regenerative Medicine. Front Bioeng Biotechnol. 2020; 8:598607.
PMID: 33381499

SATB2: A versatile transcriptional regulator of craniofacial and skeleton development, neurogenesis and tumorigenesis, and its applications in regenerative medicine.
Huang X, Chen Q, Luo W, Pakvasa M, Zhang Y, Zheng L, Li S, Yang Z, Zeng H, Liang F, Zhang F, Hu DA, Qin KH, Wang EJ, Qin DS, Reid RR, He TC, Athiviraham A, El Dafrawy M, Zhang H. SATB2: A versatile transcriptional regulator of craniofacial and skeleton development, neurogenesis and tumorigenesis, and its applications in regenerative medicine. Genes Dis. 2022 Jan; 9(1):95-107.
PMID: 35005110

FAMSi: A Synthetic Biology Approach to the Fast Assembly of Multiplex siRNAs for Silencing Gene Expression in Mammalian Cells.
He F, Ni N, Zeng Z, Wu D, Feng Y, Li AJ, Luu B, Li AF, Qin K, Wang E, Wang X, Wu X, Luo H, Zhang J, Zhang M, Mao Y, Pakvasa M, Wagstaff W, Zhang Y, Niu C, Wang H, Huang L, Shi D, Liu Q, Zhao X, Fu K, Reid RR, Wolf JM, Lee MJ, Hynes K, Strelzow J, El Dafrawy M, Gan H, He TC, Fan J. FAMSi: A Synthetic Biology Approach to the Fast Assembly of Multiplex siRNAs for Silencing Gene Expression in Mammalian Cells. Mol Ther Nucleic Acids. 2020 Dec 04; 22:885-899.
PMID: 33230483

Comprehensive classification system for multirod constructs across three-column osteotomies: a reliability study.
El Dafrawy MH, Adogwa O, Wegner AM, Pallotta NA, Kelly MP, Kebaish KM, Bridwell KH, Gupta MC. Comprehensive classification system for multirod constructs across three-column osteotomies: a reliability study. J Neurosurg Spine. 2020 Oct 09; 1-7.
PMID: 33036005

The Influence of Selective Serotonin Reuptake Inhibitors on Lumbar Arthrodesis.
Pirkle S, Bhattacharjee S, El Dafrawy M, Leucht P, Shi LL, Lee MJ. The Influence of Selective Serotonin Reuptake Inhibitors on Lumbar Arthrodesis. Clin Spine Surg. 2020 Sep 25.
PMID: 32991364

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