Lewis Shi, MD

Associate Professor of Orthopedic Surgery and Rehabilitation Medicine
Clinical Interests: Arthroscopic Shoulder Surgery, Labral Tears, Rotator Cuff Treatment, Shoulder Injuries, Shoulder Instability or Dislocation, Shoulder Replacement, Shoulder Tendonitis
Research and Scholarly Interests: Orthopaedic surgeryShoulder surgery
Websites: Department of Orthopaedic Surgery and Rehabilitation Medicine, Research Network Profile
Contact: lshi@bsd.uchicago.edu

Lewis Shi, MD, is an orthopaedic surgeon who specializes in shoulder and elbow injuries. He maximizes patients' non-operative management prior to considering surgery. If necessary, he offers minimally invasive (arthroscopic) and open procedures that are appropriate for the patient's disorders.

Dr. Shi's research focuses on the molecular basis of rotator cuff tear and biomechanics of shoulder arthritis. He also is part of several national and international multi-center studies to improve diagnostic and treatment protocols of shoulder injuries. Dr. Shi has published more than 55 peer-reviewed scientific articles and 10 book chapters.

In addition to his clinical and research work, Dr. Shi teaches medical students, residents and fellows. He has won numerous teaching awards and values his role as an educator secondary only to his role as the patient's advocate.

Harvard Shoulder and Elbow Fellowship
Boston, MA
- Shoulder/Elbow surgery
2012

Harvard Combined Orthopaedic Surgery Residency Program
Boston, MA
- Orthopaedic surgery
2011

Harvard Medical School
Boston, MA
MD
2006

Harvard College
Cambridge, MA
AB
2000
Advancing transistor-based point-of-care (POC) biosensors: additive manufacturing technologies and device integration strategies for real-life sensing.
Advancing transistor-based point-of-care (POC) biosensors: additive manufacturing technologies and device integration strategies for real-life sensing. Nanoscale. 2025 Apr 17; 17(16):9804-9833.
PMID: 40171618

An Intervertebral Disc (IVD) Regeneration Model Using Human Nucleus Pulposus Cells (iHNPCs) and Annulus Fibrosus Cells (iHAFCs).
An Intervertebral Disc (IVD) Regeneration Model Using Human Nucleus Pulposus Cells (iHNPCs) and Annulus Fibrosus Cells (iHAFCs). Adv Healthc Mater. 2025 Apr; 14(10):e2403742.
PMID: 40052622

Effect of Antifibrotic Medications on Development of Postoperative Adhesive Capsulitis and Need for Manipulation Under Anesthesia Following Total Shoulder Arthroplasty.
Effect of Antifibrotic Medications on Development of Postoperative Adhesive Capsulitis and Need for Manipulation Under Anesthesia Following Total Shoulder Arthroplasty. J Am Acad Orthop Surg Glob Res Rev. 2025 Feb 01; 9(2).
PMID: 39899748

Acromioclavicular joint injuries: multicenter expert consensus study using the Delphi method.
Acromioclavicular joint injuries: multicenter expert consensus study using the Delphi method. J Shoulder Elbow Surg. 2025 Jan 20.
PMID: 39842657

Dermal fibroblast-derived extracellular matrix (ECM) synergizes with keratinocytes in promoting re-epithelization and scarless healing of skin wounds: Towards optimized skin tissue engineering.
Dermal fibroblast-derived extracellular matrix (ECM) synergizes with keratinocytes in promoting re-epithelization and scarless healing of skin wounds: Towards optimized skin tissue engineering. Bioact Mater. 2025 May; 47:1-17.
PMID: 39872210

Utility of radiographs for asymptomatic patients following primary anatomic and reverse total shoulder arthroplasty.
Utility of radiographs for asymptomatic patients following primary anatomic and reverse total shoulder arthroplasty. J Shoulder Elbow Surg. 2025 Jan 03.
PMID: 39756641

Effective Bone Tissue Fabrication Using 3D-Printed Citrate-Based Nanocomposite Scaffolds Laden with BMP9-Stimulated Human Urine Stem Cells.
Effective Bone Tissue Fabrication Using 3D-Printed Citrate-Based Nanocomposite Scaffolds Laden with BMP9-Stimulated Human Urine Stem Cells. ACS Appl Mater Interfaces. 2025 Jan 08; 17(1):197-210.
PMID: 39718997

Engrailed-1 inactivation leads to scarless skin wound healing through extracellular matrix remodeling.
Engrailed-1 inactivation leads to scarless skin wound healing through extracellular matrix remodeling. Genes Dis. 2025 May; 12(3):101484.
PMID: 39926330

Establishment and characterization of a rat model of scalp-cranial composite defect for multilayered tissue engineering.
Establishment and characterization of a rat model of scalp-cranial composite defect for multilayered tissue engineering. Int J Surg. 2024 Dec 01; 110(12):8233-8237.
PMID: 39374047

Bone Marrow Aspirate Concentrate May Improve Healing and Function in Rotator Cuff Repair: A Systematic Review.
Bone Marrow Aspirate Concentrate May Improve Healing and Function in Rotator Cuff Repair: A Systematic Review. Arthroscopy. 2024 Nov 22.
PMID: 39581273
View All Publications
NIH Loan Repayment Program award
2013

Gold Medal presentation. American Roentgen Ray Society Annual Meeting.
2012

AAOS Clinical Scientist Development Program (CSDP) participant
2009

Paul Dudley White Fellowship for International Research
Harvard Medical School
2001

Community Service Award
Harvard Medical School
2001

Magna Cum Laude with Highest Honors
Harvard College
2000

Phi Beta Kappa
Harvard College
1999

Derek Bok Award for Distinguished Teaching
1999 - 2000

Lewis Shi, MD

Education & Training

Publications

Honors & Awards