Rex C. Haydon, MD PhD

Rex Haydon, MD, PhD, focuses on the comprehensive treatment of malignant and benign tumors in bone or soft tissue. He specializes in the surgical care of bone and soft tissue tumors, including limb-salvage and reconstructive surgery of the upper and lower extremities. Dr. Haydon works with an integrated team of specialists to ensure that patients have access to the most innovative and effective treatment options available.



Also a skilled physician scientist, his research focuses on advancing the treatment of musculoskeletal tumors. Dr. Haydon has a particular interest in the underlying causes of musculoskeletal neoplasms. Author of more than 25 articles and book chapters, he has accepted career development awards from both the Orthopaedic Research and Education Foundation and the National Institutes of Health. Additionally, Dr. Haydon's research has been supported by the Musculoskeletal Tumor Foundation.

The University of Chicago
Chicago, Illinois
Orthopaedic Fellowship - Oncology
2003

The University of Chicago
Chicago, Illinois
Orthopaedic Fellowship - Research
2002

The University of Chicago
Chicago, Illinois
Resident - Orthopaedic Surgery
2001

The University of Chicago
Chicago, Illinois
Ph.D - Anthropology
1996

The University of Chicago
Chicago, Illinois
M.A. - MAPSS (Social Sciences),
1993

The University of Chicago
Chicago, Illinois
B.A. - Anthropology
1988

A simplified noncryogenic strategy to transport mesenchymal stem cells: Potential applications in cell therapy and regenerative medicine.
A simplified noncryogenic strategy to transport mesenchymal stem cells: Potential applications in cell therapy and regenerative medicine. Genes Dis. 2024 May; 11(3):101073.
PMID: 38274386

The evolving roles of Wnt signaling in stem cell proliferation and differentiation, the development of human diseases, and therapeutic opportunities.
The evolving roles of Wnt signaling in stem cell proliferation and differentiation, the development of human diseases, and therapeutic opportunities. Genes Dis. 2024 May; 11(3):101026.
PMID: 38292186

Correction: BMP9-regulated angiogenic signaling plays an important role in the osteogenic differentiation of mesenchymal progenitor cells.
Correction: BMP9-regulated angiogenic signaling plays an important role in the osteogenic differentiation of mesenchymal progenitor cells. J Cell Sci. 2023 Jun 01; 136(11).
PMID: 37272422

Bone Morphogenic Protein 9 (BMP9)/Growth Differentiation Factor 2 (GDF2) modulates mouse adult hippocampal neurogenesis by regulating the survival of early neural progenitors.
Bone Morphogenic Protein 9 (BMP9)/Growth Differentiation Factor 2 (GDF2) modulates mouse adult hippocampal neurogenesis by regulating the survival of early neural progenitors. Genes Dis. 2023 Jul; 10(4):1175-1179.
PMID: 37397531

Canonical and noncanonical Wnt signaling: Multilayered mediators, signaling mechanisms and major signaling crosstalk.
Canonical and noncanonical Wnt signaling: Multilayered mediators, signaling mechanisms and major signaling crosstalk. Genes Dis. 2024 Jan; 11(1):103-134.
PMID: 37588235

Long noncoding RNA (lncRNA) H19: An essential developmental regulator with expanding roles in cancer, stem cell differentiation, and metabolic diseases.
Long noncoding RNA (lncRNA) H19: An essential developmental regulator with expanding roles in cancer, stem cell differentiation, and metabolic diseases. Genes Dis. 2023 Jul; 10(4):1351-1366.
PMID: 37397543

Corrigendum to "Characterization of the essential role of bone morphogenetic protein 9 (BMP9) in osteogenic differentiation of mesenchymal stem cells (MSCs) through RNA interference" [Genes & Diseases 5(2018):172-184].
Corrigendum to "Characterization of the essential role of bone morphogenetic protein 9 (BMP9) in osteogenic differentiation of mesenchymal stem cells (MSCs) through RNA interference" [Genes & Diseases 5(2018):172-184]. Genes Dis. 2023 Mar; 10(2):632-637.
PMID: 37223525

Corrigendum to 'Modeling colorectal tumorigenesis using the organoids derived from conditionally immortalized mouse intestinal crypt cells (ciMICs)' [Genes Dis 8 (2021) 814-826].
Corrigendum to 'Modeling colorectal tumorigenesis using the organoids derived from conditionally immortalized mouse intestinal crypt cells (ciMICs)' [Genes Dis 8 (2021) 814-826]. Genes Dis. 2023 Mar; 10(2):618-619.
PMID: 37223499

Corrigendum to "The development of a sensitive fluorescent protein-based transcript reporter for high throughput screening of negative modulators of lncRNAs" [Genes & Diseases 5 (2018) 62-74].
Corrigendum to "The development of a sensitive fluorescent protein-based transcript reporter for high throughput screening of negative modulators of lncRNAs" [Genes & Diseases 5 (2018) 62-74]. Genes Dis. 2023 Mar; 10(2):627-629.
PMID: 37223508

Corrigendum to "Establishment and functional characterization of the reversibly immortalized mouse glomerular podocytes (imPODs)" [Genes & Diseases 5 (2018) 137-149].
Corrigendum to "Establishment and functional characterization of the reversibly immortalized mouse glomerular podocytes (imPODs)" [Genes & Diseases 5 (2018) 137-149]. Genes Dis. 2023 Mar; 10(2):630-631.
PMID: 37223498

View All Publications

Orlov Visiting Professor in Orthopaedic Oncology
Loyola University of Chicago
2018

Senior Faculty Scholar
Bucksbaum Institute for Clinical Excellence
2017

Gerald S. Laros Resident Teaching Award
2011

Keynote Speaker
Pritzker School of Medicine White Coat Ceremony
2010

American-British-Canadian Traveling Fellowship, AOA
2009

Induction into ??? (Beta Chapter) as Faculty member by Pritzker School of Medicine
2008

Gerald S. Laros Resident Teaching Award
2007

Orthopaedic Research Society Career Development Award
2006

Kappa Delta Ann Doner Vaughan Award, Co-Recipient, AAOS/ORS
2006

Marshall R. Urist Young Investigator Award, Association of Bone & Joint Surgeons
2006

John J. Fahey, MD Memorial North American Traveling Fellowship, AOA
2005

K08 Mentored Clinical Scientist Development Award, NIH-NIAMS
2004 - 2009

Thomas M. Coffman OREF Career Development Award
2003 - 2005

Best Poster Award: Charles Huggins Conference: “Upregulation Of cKit In Giant Cell Tumor of Bone: Po
2002

Howard Schneider Award for Best Manuscript at the OREF Midwest Conference
2000